Case Report: An Acquired Hemophilia A Revealing a Rheumatoid Arthritis
Publisher : PJPCR
Author(s)
Manasi S.
Abstract
Acquired hemophilia A (AH) is a rare autoimmune hemorrhagic disorder caused by anti-factor VIII autoantibodies. Although typically associated with neoplasia or idiopathic causes, its association with rheumatoid arthritis (RA) remains rare. This case report describes a 58-year-old male patient presenting with severe hemorrhagic manifestations—including digestive hemorrhage and subsequently intracranial hemorrhage—whose diagnosis of acquired hemophilia A led to the discovery of underlying rheumatoid arthritis. Management with corticosteroids, methotrexate, and rituximab resulted in clinical improvement and normalization of coagulation parameters. This case highlights the importance of considering RA in the etiological investigation of acquired hemophilia A and demonstrates the need for regular monitoring to detect associated systemic diseases.