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Case Report: An Acquired Hemophilia A Revealing a Rheumatoid Arthritis

Case Report: An Acquired Hemophilia A Revealing a Rheumatoid Arthritis

Publisher : PJPCR
Author(s)
Manasi S.
Abstract

Acquired hemophilia A (AH) is a rare autoimmune hemorrhagic disorder caused by anti-factor VIII autoantibodies. Although typically associated with neoplasia or idiopathic causes, its association with rheumatoid arthritis (RA) remains rare. This case report describes a 58-year-old male patient presenting with severe hemorrhagic manifestations—including digestive hemorrhage and subsequently intracranial hemorrhage—whose diagnosis of acquired hemophilia A led to the discovery of underlying rheumatoid arthritis. Management with corticosteroids, methotrexate, and rituximab resulted in clinical improvement and normalization of coagulation parameters. This case highlights the importance of considering RA in the etiological investigation of acquired hemophilia A and demonstrates the need for regular monitoring to detect associated systemic diseases.

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Copyright © Princeton Journal of Pre-Collegiate Research. All rights reserved

Copyright © Princeton Journal of Pre-Collegiate Research. All rights reserved

Copyright © Princeton Journal of Pre-Collegiate Research. All rights reserved